The rising reputation of NMN as a supplement to slow down aging stems from a lot of scientific research showing that NMN can slow down aging, and by good claims about NMN as a longevity ingredient by effectively-recognized researchers, like Professor David Sinclair from Harvard University, Professor Shin-ichiro Imai from Washington University, and a lot of other individuals (R,R,R,R,R).
So now you can acquire NMN supplements everywhere.
On the other hand, this significantly elevated demand lead also to unscrupulous sellers to give low-purity NMN supplements, or even NMN supplements that do not contain NMN.
Difficulties with NMN supplements
Some NMN supplements claim to be “high-purity NMN,” although they are in reality low-purity NMN. Some NMN supplements even have much less than 80 percent purity.
Also, what nmn 日本 contains is not known to buyers. It can be just fillers like flour (employed to lower the price), or it could be toxic substances developed as a by-item from the NMN production course of action.
There are even “NMN supplements” that do not contain NMN, but alternatively contain nicotinamide (a B vitamin that looks somewhat like NMN but has full distinctive effects in the physique), or that contain nicotinamide riboside (NR).
NR is not the similar as NMN. There are numerous factors to believe that NMN is better than NR. We explain in this blog post why.
Given the extremely higher manufacturing costs of NMN (it’s one of the most high priced meals supplements to make) some NMN supplement sellers adulterate their products to lower the costs and make additional profit.
How to discover the best NMN supplement?
So how can you find the ideal NMN supplement? And make sure the supplement is a trustworthy, fantastic high-quality one?
You would require to pay focus to the following items:
1. The NMN corporation has esteemed scientific advisors
Make positive your NMN supplement is from a company that has leading longevity scientists in its advisory board, and operates with scientific consultants that are renowned in the field of aging.
You can google these researchers to see if they are connected to a university or lab, and check on PubMed how lots of research they have published.
That way you can make sure they are active, effectively-trustworthy scientists. We at NOVOS have such top experts as board members and advisors.
2. Be skeptical of “high-purity” NMN claims
Obtain a high-purity (containing extra than 99 % NMN) supplement, so not 1 that has been adulterated with other substances.
However, be skeptical of so called “99 % purity” NMN supplements. Often, the purity is measured subjectively, and not in an absolute way.
Generally, the “purity” is measured by comparing the supplement with other supplements that are significantly less pure. In this way one particular can claim incredibly high “purities”.
Having said that, to establish the actual purity, a single demands to calculate the purity in an objective manner, by measuring the absolute purity of the supplement itself.
Or, when measuring relative purity by comparing NMN with a gold standard of NMN, the brand’s purity really should be additional than one hundred percent pure (e.g. 101 percent purity). This signifies the NMN is a lot more pure than the gold standard.
three. Make certain it’s stable, new-generation NMN
Did you know that not al NMN is the exact same?
Newer generation NMN is a lot more steady. NMN is a fragile molecule that when exposed to water molecules can get converted into nicotinamide (NAM).
The stability of NMN is largely determined by the surrounding water molecules, and the organization of the NMN with other surrounding NMN molecules. The water molecules are polar (obtaining distinct electric charges on various sides), which can effect the electron configuration of the NMN molecule and lead to less stability.
NMN molecules that are extra orderly organized and more compactly arranged suffer less from the destabilizing interaction with water molecules both in the solution and with water from air. In addition, developing far more “high-density” NMN by reducing water content material improves stability.
We at NOVOS give this type of subsequent-generation, more steady NMN.
The NMN in NOVOS Increase arranges itself into spherical crystals (as opposed to sawtooth crystals), which are a lot more capable of blocking make contact with with humidity in the air, which increases the stability and shelf life of our NMN. Compared to sawtooth crystal shapes, the spherical crystal is far more ordered, compact and as a result every NMN molecule will have significantly less exposure to air and water.
There exists even far more crystalline NMN (and NMN derivatives), which includes precise organization of the NMN molecules, for which David Sinclair’s business MetroBiotech has filed patents. See for instance this patent. Nevertheless, this is likely overkill.
four. Third celebration-lab testing of NMN
Make certain NMN supplement seller has worked with each other with third party labs that checked the supplement for contaminants such as:
Heavy metals (e.g. lead, arsenic, cadmium and mercury)
Bacteria (e.g. E coli, S aureus, Salmonella)
Yeast and mold
Toxins (e.g. toluene, xylenes, trichloroethylene, isopropyl alcohol, ethylene oxide, ethyl ether, acetone, benzene, chloroform, acetonitrile, etc). Toluene is an essential contaminant that requires to checked.
Be aware, some businesses only test heavy metals, but not microorganisms like yeast and bacteria, or only test for microorganisms and not for heavy metals.
Make certain your NMN supplement has been third-celebration tested by independent testing solutions to confirm purity and safety. A lot of sellers of NMN supplements use less effectively-identified and much less reputed testing organizations.
five. The NMN is effectively manufactured
Make sure your NMN supplement is developed in a facility that functions according to GMP (Very good Manufacturing Practices) and to the most recent ISO norms.
Also, the production procedure of NMN requires to be state-of-the-art.
This indicates for instance that the pH and water content in the course of the production process ought to be incredibly effectively controlled. A also acid or as well alkaline environment will break the electric balance of the NMN crystals. NOVOS Boost NMN is pH balanced, which improves the internal structure and stability of the crystals throughout production. Further, the water content in the crystals is controlled in the course of production, which additional improves the NMN’s stability.
It’s crucial to use in this method novel-generation NMN made of spherical crystals, which has greater bulk density and fluidity, avoiding unstable dosages due to raising dust in the production method.
Why NOVOS’ NMN is unique
NOVOS Enhance is a exclusive NMN supplement adhering to all of the above.
We use rigorous science, work with each other with the prime scientific specialists in the aging field, do due diligence and conduct trustworthy substantial testing to make positive you have the most effective high-high quality NMN supplement, which pairs excellently with our foundational formulation, NOVOS Core.
Also, our NMN is next-generation NMN that is much more steady.
NOVOS’ NMN is third-party tested, higher-purity NMN. Our NMN is likely the most thoroughly tested NMN on the marketplace: We test for far extra contaminants than a lot of other companies do.